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    1. Membrane Transporter/Ion Channel
    2. Calcium Channel

    Calcium Channel

    Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels. Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further reduce blood pressure, relieve chest pain (angina) and control an irregular heartbeat.

    Calcium Channel 相关产品 (113):

    Cat. No. Product Name Effect Purity
    • HY-B0470
      Neomycin sulfate Inhibitor >98.0%
      Neomycin sulfate是用于预防或治疗 细菌 感染的氨基糖苷类抗生素。
    • HY-A0064
      Verapamil hydrochloride Antagonist 99.95%
      Verapamil hydrochloride 是钙离子通道 (calcium channel) 拮抗剂。
    • HY-B0284
      Nifedipine Antagonist
      Nifedipine (BAY-a-1040) 是有效的钙离子通道 (calcium channel) 阻滞剂,常用于治疗心肌功能不全。
    • HY-13434
      Ionomycin >98.0%
      Ionomycin (SQ23377) 是一个钙离子载体 (Calcium ionophore),也是来源于链霉菌属 (Streptomyces conglobatus ATCC 31005) 的一种抗生素。
    • HY-B0282
      Acetylcholine chloride Activator >98.0%
      Acetylcholine (chloride) 是在中枢和外周神经系统中常见的神经递质
    • HY-13433
      Thapsigargin Inhibitor >99.0%
      Thapsigargin 是一种微粒体 Ca2+-ATPase 抑制剂。
    • HY-Z0816
      Dehydronitrosonisoldipine Antagonist 98.79%
      Dehydronitrosonisoldipine 是钙离子通道的拮抗剂。
    • HY-14744A
      Levamlodipine besylate Inhibitor 99.91%
      Levamlodipine besylate ((S)-Amlodipine besylate) 是一种功能强大的二氢吡啶钙通道 (calcium channel) 阻滞剂,具有舒张血管的作用,可用于高血压、心绞痛的治疗。
    • HY-15553A
      Mibefradil dihydrochloride Inhibitor 99.63%
      Mibefradil dihydrochloride 是一种钙离子通道 (calcium channel) 抑制剂,选择性作用于 T 型 Ca2+通道,作用于 T 型和 L 型通道,IC50 分别为 2.7 μM 和 18.6 μM。
    • HY-B0265
      Nimodipine Inhibitor 99.87%
    • HY-15124
      Bay-K-8644 ((S)-(-)-) Agonist 98.34%
      Bay-K-8644 (S)-(-)- 是 L 型钙离子通道激动剂。Bay-K-8644 (S)-(-)- 激活 Ba2+电流 (IBa),EC50 为 32 nM。
    • HY-101455
      CDN1163 Activator 99.12%
      CDN1163 是一种肌肉/内质网 Ca2 +-ATPase (SERCA) 激活剂。
    • HY-12542A
      Dantrolene sodium hemiheptahydrate Inhibitor >98.0%
      Dantrolene钠盐水合物是一种钙通道蛋白抑制剂, 抑制钙离子从肌浆释放, Dantrolene钠盐水合物是一种骨骼肌松弛药。
    • HY-B0320A
      Cromolyn sodium Inhibitor 99.97%
      Cromolyn (sodium) 是抗过敏化合物。
    • HY-14656
      Diltiazem hydrochloride Antagonist 98.39%
      Diltiazem hydrochloride是钙离子流入抑制剂(缓慢通道阻断剂或钙拮抗剂)。
    • HY-B1221
      Flufenamic acid Inhibitor 99.92%
      Flufenamic acid 是一种非甾体类抗炎剂,能够抑制 COX 的活性,激活 AMPK 的活性,调节离子通道,阻滞氯离子通道 (chloride channel) 和 L-型钙离子通道 (L-type Ca2+ channel),调节非选择性阳离子通道,激活钾离子通道 (K+ channel) 等。
    • HY-17401
      Ranolazine dihydrochloride Inhibitor 99.92%
    • HY-B0317
      Amlodipine Antagonist 99.57%
    • HY-N0215
      L-Phenylalanine Antagonist 98.06%
      L-Phenylalanine是_alpha_2_delta_钙离子通道拮抗剂,Ki为980 nM。
    • HY-13764
      Tetrandrine Inhibitor 99.90%
      Tetrandrine (NSC-77037) 是一种双苯基异喹啉生物碱,抑制电压门控钙离子通道 (ICa) 和 Ca2+ 激活的钾离子通道。
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