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    1. GPCR/G Protein
    2. Cholecystokinin Receptor

    Cholecystokinin Receptor

    Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the GI tract and the brain, respectively, as well as in other organs. In mammals, CCK/CCKAR interactions affect a number of immunological parameters, including regulation of lymphocytes and functioning of monocytes.

    CCK, also known as pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum. The main function of CCK is to cause the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also induces drug tolerance to opioids like morphine and heroin. Cholecystokinin (CCK) has strong bioactivity in the regulation of a number of cell activities.

    Cholecystokinin Receptor 相关产品 (15):

    Cat. No. Product Name Effect Purity
    • HY-A0190
      Ceruletide Agonist 99.96%
      Ceruletide (Caerulein) 是从澳大利亚青蛙皮肤中分离的生物活性十肽,一种有效的胆囊收缩剂,为缩胆囊素受体 (cholecystokinin receptor) 激动剂。
    • HY-P1097
      Gastrin-1, human 98.41%
      Gastrin-1, human 是胃中产生的内源性肽,通过 CCK2 受体增加胃酸的分泌。
    • HY-17617
      Nastorazepide Antagonist 99.89%
      Nastorazepide(Z-360)是一种选择性的, 口服有效的, 1,5-苯并二氮杂环衍生物胃泌素/胆囊收缩素2(CCK-2)受体拮抗剂,具有潜在的抗肿瘤活性。
    • HY-B2154
      Loxiglumide Antagonist >98.0%
      Loxiglumide 是缩胆囊素 (CCK-1) 受体拮抗剂。
    • HY-B1330
      Proglumide Antagonist 99.74%
      Proglumide 是已知的胆囊收缩素 (CCK) 拮抗剂。
    • HY-B1439B
      Lorglumide sodium salt Antagonist
      Lorglumide sodium salt (CR-1409 sodium salt) 是一种有效的胆囊收缩素(CCK)受体拮抗剂。
    • HY-14850
      Sograzepide Antagonist 98.01%
      Sograzepide (Netazepide;YF476) 是一种胃泌素/缩胆囊素2受体 (gastrin/cholecystokinin 2 receptor (CCK2)) 拮抗剂。
    • HY-U00062
      Tarazepide Antagonist
      Tarazepide 是一种有效且特异性的 CCK-A 受体拮抗剂。
    • HY-P1593
      Mini Gastrin I, human
      Mini Gastrin I, human 为由 13 个氨基酸组成的短的人胃泌素 1 (gastrin 1),能够与 CCK2i4sv 受体结合。
    • HY-U00387
      CCK-A receptor inhibitor 1 Inhibitor
      CCK-A receptor inhibitor 1 是一种缩胆囊素 A (cholecystokinin A, CCK-A) 受体抑制剂,IC50 为 340 nM。
    • HY-U00363
      CHEMBL333994 Antagonist
      CHEMBL333994 是一种有口服活性的,缩胆囊素 A (CCK-A) 的有效拮抗剂,其 IC50 值为 0.67 nM。
    • HY-11076
      GI 181771 Agonist
      GI 181771是研究用于治疗肥胖症的胆囊收缩素1 (cholecystokinin 1) 受体激动剂。
    • HY-U00375
      Gastrin/CCK antagonist 1 Antagonist
      Gastrin/CCK antagonist 1 是 gastrin/CCK 的拮抗剂,可用于肠胃失调疾病的研究。
    • HY-11077
      SR 146131 Agonist
      SR 146131是一种有效,有口服活性,选择性的非多肽缩胆囊素1 (cholecystokinin 1)受体激动剂。
    • HY-U00360
      CCK-B Receptor Antagonist 1 Antagonist
      CCK-B Receptor Antagonist 1 是一种缩胆囊素 B (CCK-B) 受体拮抗剂,具有减少胃酸分泌的潜能。
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