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    1. Protein Tyrosine Kinase/RTK
    2. Ephrin Receptor

    Ephrin Receptor

    Ephrin receptors (Ephs) are a group of receptors that are activated in response to binding ephrin. Ephs form the largest known subfamily of receptor tyrosine kinases (RTKs). Both Ephs and their corresponding ephrin ligands are membrane-bound proteins that require direct cell-cell interactions for Eph receptor activation. Eph/ephrin signaling has been implicated in the regulation of a host of processes critical to embryonic development including axon guidance, formation of tissue boundaries, cell migration, and segmentation. Additionally, Eph/epherin signaling has recently been identified to play a critical role in the maintenance of several processes during adulthood including long-term potentiation, angiogenesis, and stem cell differentiation and cancer. The ability of Ephs and ephrins to mediate a variety of cell-cell interactions places the Eph/ephrin system in an ideal position to regulate a variety of different biological processes during embryonic development.

    Ephrin Receptor 相关产品 (4):

    Cat. No. Product Name Effect Purity
    • HY-18007
      ALW-II-41-27 Inhibitor 99.38%
      ALW-II-41-27是 Eph 家族酪氨酸激酶抑制剂,抑制Eph2的 IC50为11 nM。
    • HY-13314
      Tesevatinib Inhibitor 99.21%
      Tesevatinib (XL-647) 是口服可用的多靶点酪氨酸激酶抑制剂; 抑制EGFRErbB2KDRFlt4EphB4 激酶活性的 IC50 值分别为 0.3,16,1.5,8.7,和1.4 nM。
    • HY-13258
      NVP-BHG712 Inhibitor 99.51%
      NVP-BHG712是EphB4抑制剂,ED50为25 nM,对c-Raf,c-Src和c-Abl的IC50分别为0.395 μM,1.266 μM和1.667 μM。
    • HY-16265
      JI-101 Inhibitor 99.95%
      JI-101是有口服活性的有抗癌活性的多靶点激酶抑制剂,可抑制 VEGFR2PDGFRβEphB4
    Isoform Specific Products

    Your Search Returned No Results.

    Sorry. There is currently no product that acts on isoform together.

    Please try each isoform separately.