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    1. Protein Tyrosine Kinase/RTK
    2. Itk

    Itk

    Itk (Interleukin-2-inducible T-cell kinase) is a member of the TEC family of kinases and is highly expressed in T cells. Itk plays a role in T-cell proliferation, differentiation, cytokine release and chemotaxis. Itk is functionally important for the development and effector function of Th2 and Th17 cells. Itk is an attractive target for the treatment of T-cell-mediated inflammatory diseases.

    Itk 相关产品 (5):

    Cat. No. Product Name Effect Purity
    • HY-11092
      BMS-509744 Inhibitor 98.02%
      BMS-509744是有效,选择性的 Itk 激酶抑制剂,IC50值为19 nM。
    • HY-12680
      PRN694 Inhibitor 99.44%
      PRN694 是一种高度选择且有效的 T 细胞激酶 (ITK) 和静息淋巴细胞激酶 (RLK) 的共价抑制剂,其 IC50 值分别为 0.3 和 1.4 nM。
    • HY-109078
      Vecabrutinib Inhibitor 99.96%
      Vecabrutinib 是一种有效的,非共价的 BTKITK 抑制剂,Kd 值分别为 0.3 nM 和 2.2 nM;Vecabrutinib 对 ITK 的 IC50 值为 24 nM。
    • HY-11066
      ITK inhibitor Inhibitor
      ITK抑制剂是ITK的高活性抑制剂。
    • HY-16984
      GNE-4997 Inhibitor
      GNE-4997 是一种有效且有选择性的 ITK/TSK 抑制剂。
    Isoform Specific Products

    Your Search Returned No Results.

    Sorry. There is currently no product that acts on isoform together.

    Please try each isoform separately.

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