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    1. Membrane Transporter/Ion Channel
    2. Monoamine Transporter

    Monoamine Transporter

    Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. Three major classes of MATs (SERT, DAT, NET) are responsible for the reuptake of their associated amine neurotransmitters (serotonin, dopamine, norepinephrine). MATs are located just outside the synaptic cleft (peri-synaptically), transporting monoamine transmitter overflow from the synaptic cleft back to the cytoplasm of the pre-synaptic neuron. MAT regulation generally occurs throughphosphorylation and posttranslational modification. Due to their significance in neuronal signaling, MATs are commonly associated with drugs used to treat mental disorders as well as recreational drugs. Compounds targeting MATs range from medications such as the wide variety of tricyclic antidepressants, selective serotonin reuptake inhibitors to stimulantmedications and amphetamine.

    Monoamine Transporter 相关产品 (11):

    Cat. No. Product Name Effect Purity
    • HY-N0480
      Reserpine Inhibitor 99.83%
      Reserpine 是囊泡单胺转运蛋白 2 (VMAT2) 的抑制剂。
    • HY-15793
      NBI-98782 Inhibitor 98.36%
    • HY-B0590B
      Tetrabenazine ((+)-) Inhibitor 99.81%
      Tetrabenazine ((+)-)是一个可逆转的VMAT-2的抑制剂。
    • HY-B0590
      Tetrabenazine Inhibitor 99.10%
    • HY-B0590A
      Tetrabenazine Racemate Inhibitor >98.0%
      Tetrabenazine (Racemate)是一个有选择性和可逆转的VMAT-2抑制剂。
    • HY-N0480A
      Reserpine hydrochloride Inhibitor 99.84%
      Reserpine (hydrochloride) 是囊泡单胺转运蛋白 2 (VMAT2) 的抑制剂。
    • HY-101416
      Vanilpyruvic acid >98.0%
      Vanilpyruvic acid是儿茶酚胺代谢物和香草酸的前体。
    • HY-B0590S
      Tetrabenazine D6 Inhibitor >99.0%
      Tetrabenazine D6是Tetrabenazine的氘代化合物标准品。
    • HY-17590
      Radafaxine hydrochloride Inhibitor 99.47%
    • HY-15793A
      NBI-98854 Inhibitor
    • HY-B0590S1
      (+)-Tetrabenazine D6
      (+)-Tetrabenazine D6 是 (+)-Tetrabenazine 的氘代化合物标准品。(+)-Tetrabenazine 是一种不可逆的 vesicular monoamine transporter 2 抑制剂。
    Isoform Specific Products

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